Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15700707 | 0.86 | MAPT (0.52) | NCF1SLC22A12MAPTKDM4ENPC1 | |
| SCHEMBL6248338 | 0.80 | NCF1 (0.47) | NCF1LOXL2SLC22A12HTR1AADRA1D | |
| SCHEMBL21082253 | 0.79 | NCF1 (0.50) | NCF1LOXL2SLC22A12HTR1AADRA1D | |
| SCHEMBL21852297 | 0.79 | NCF1 (0.46) | NCF1LOXL2SLC22A12HTR1AADRA1D | |
| SCHEMBL2816694 | 0.79 | LOXL2 (0.47) | NCF1LOXL2SLC22A12HTR1AADRA1D | |
| SCHEMBL3790696 | 0.76 | SLC22A12 (0.49) | SLC22A12MAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL27997805 | 0.76 | NCF1 (0.56) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL28446212 | 0.75 | ALDH1A1 (0.38) | NCF1HTR2CHTR2BMAPTKDM4E | |
| SCHEMBL22288152 | 0.73 | KDM4E (0.45) | NCF1MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL8908139 | 0.73 | HTR1A (0.47) | NCF1LOXL2SLC22A12HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023027630-A9 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-07-27 | — | — | WO | claimed |
| WO-2023027630-A2 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-03-02 | — | — | WO | claimed |
| WO-2023027630-A9 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023027630-A2 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-03-02 | — | — | WO | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| WO-2022089406-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海青煜医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |
| WO-2021107872-A1 | COMPOSITES, METHODS AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-06-03 | — | — | WO | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| WO-2020072656-A1 | IMIDOZOPYRIMIDINE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| US-20090215766-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION | 2009-08-27 | — | — | US | disclosed |
| US-20090215766-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION | 2009-08-27 | — | — | US | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215766-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | JAK1, JAK2, JAK3 | NCF1 1036/4885LOXL2 2849/4885SLC22A12 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.