Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736492 | 0.83 | CHRNA7 (0.42) | KCNH2CYP2D6OPRD1SIGMAR1OPRM1 | |
| SCHEMBL22313912 | 0.81 | OPRM1 (0.39) | KCNH2SIGMAR1OPRM1 | |
| SCHEMBL738548 | 0.77 | FASN (0.41) | SIGMAR1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL14720614 | 0.76 | FASN (0.40) | SIGMAR1OPRM1CHRNA7 | |
| SCHEMBL22288471 | 0.76 | OPRM1 (0.36) | KCNH2SIGMAR1OPRM1CHRNA7 | |
| SCHEMBL3224637 | 0.74 | HTR2A (0.35) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL3222393 | 0.73 | HTR2A (0.34) | SIGMAR1CHRNA7 | |
| SCHEMBL17317176 | 0.73 | OPRM1 (0.48) | KCNH2SIGMAR1OPRM1 | |
| SCHEMBL11368679 | 0.72 | MEN1 (0.35) | OPRM1CHRNA7 | |
| SCHEMBL22314195 | 0.71 | OPRM1 (0.31) | KCNH2OPRD1SIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157026-A1 | HYDROXYLATED DERIVATIVES OF 1-OXA-4,9-DIAZASPIRO UNDECANE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-08-06 | — | — | WO | disclosed |