SCHEMBL22289409

SCHEMBL22289409

C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCC[PH](=O)OCC[N+](C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
ACHE P22303 3/20 0.42
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
THRB P10828 1/20 0.39
APEX1 P27695 2/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CHRM5 P08912 3/20 0.38
CHRM1 P11229 3/20 0.38
CHRM3 P20309 3/20 0.38
ALDH1A1 P00352 1/20 0.37
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PGR P06401 1/20 0.36
HTR1A P08908 1/20 0.36
CHRNB2 P17787 1/20 0.36
TBXA2R P21731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80351 0.92 CHRM5 (0.44) TSHRACHETHRBAPEX1CHRM5
SCHEMBL14988989 0.89 TSHR (0.45) TSHRACHETHRBAPEX1POLB
SCHEMBL1260104 0.88 TSHR (0.47) TSHRACHERAD52NPSR1THRB
SCHEMBL5673775 0.86 TSHR (0.50) TSHRACHERAD52NPSR1THRB
SCHEMBL1260812 0.86 TSHR (0.50) TSHRACHERAD52NPSR1THRB
Methacrylic Acid SCHEMBL5607196 0.86 CHRM5 (0.40) TSHRACHETHRBAPEX1POLB
Hydrochloric Acid SCHEMBL6114873 0.84 TSHR (0.66) TSHRACHERAD52NPSR1THRB
SCHEMBL21485156 0.84 TSHR (0.39) TSHRACHETHRBCHRM5CHRM1
SCHEMBL3518542 0.84 THRB (0.47) TSHRACHETHRBAPEX1POLB
SCHEMBL16227465 0.81 CHRM5 (0.39) TSHRACHEAPEX1CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-218674615-U PQ-51 solid content rapid automatic tester 江苏博恩尼科生物技术有限公司 2023-03-21 CN disclosed
CN-115109188-A Method for preparing polyquaternium-51 by using micro-jet mixer-microchannel reactor-tubular reactor 江苏博恩尼科生物技术有限公司 2022-09-27 CN disclosed
US-20200330653-A1 MEDICAL DEVICE AGC Inc. (JP) 2020-10-22 US disclosed
WO-2020158908-A1 TOPICAL COMPOSITION ロート製薬株式会社 2020-08-06 WO disclosed