Methacrylic Acid

Methacrylic Acid

SCHEMBL5607196

C=C(C)C(=O)OCC[PH](=O)OCC[N+](C)(C)C.C=C(C)C(=O)[O-]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 5/20 0.40
CHRM1 P11229 5/20 0.40
CHRM3 P20309 5/20 0.40
CHRM2 P08172 4/20 0.38
CHRM4 P08173 4/20 0.38
CHRNB2 P17787 3/20 0.38
CHRNA7 P36544 3/20 0.38
CHRNA4 P43681 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTR1A P08908 2/20 0.38
PGR P06401 1/20 0.38
TBXA2R P21731 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA10 Q9GZZ6 1/20 0.38
CHRNA9 Q9UGM1 1/20 0.38
GALR3 O60755 2/20 0.37
THRB P10828 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80351 0.94 CHRM5 (0.44) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL22289409 0.86 TSHR (0.51) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL3518542 0.86 THRB (0.47) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL14988989 0.86 TSHR (0.45) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL1260104 0.84 TSHR (0.47) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL21485156 0.84 TSHR (0.39) CHRM5CHRM1CHRM3THRBTSHR
Methacrylic Acid SCHEMBL21931217 0.83 CHRM5 (0.57) CHRM5CHRM1CHRM3CHRM2CHRM4
Methacrylic Acid SCHEMBL2511701 0.83 CHRM5 (0.57) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL5673775 0.83 TSHR (0.50) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL1260812 0.83 TSHR (0.50) CHRM5CHRM1CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7311980-B1 Polyactive/polylactic acid coatings for an implantable device ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-12-25 US disclosed
EP-1641433-A1 NOVEL DERMATOLOGICAL AND/OR COSMETOLOGIC HYDRATING AND ANTI-IRRITATION COMPOSITIONS Laboratoire Biorga (FR) 2006-04-05 EP disclosed
WO-2004041235-A1 NOVEL DERMATOLOGICAL AND/OR COSMETOLOGIC HYDRATING AND ANTI-IRRITATION COMPOSITIONS LABORATOIRE BIORGA (FR) 2004-05-21 WO disclosed