SCHEMBL2228963

SCHEMBL2228963

C1=CCC(N2CCCC2)C1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 13/20 0.41
L3MBTL1 Q9Y468 12/20 0.41
FYN P06241 1/20 0.38
MBTD1 Q05BQ5 5/20 0.37
HTR6 P50406 1/20 0.36
TP53BP1 Q12888 2/20 0.34
L3MBTL4 Q8NA19 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228357 0.97 FYN (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL2227496 0.82 L3MBTL3 (0.39) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL737061 0.81
SCHEMBL2227575 0.80 KDM4E (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL14838336 0.80 KDM4E (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL735437 0.79 FYN (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL735922 0.79 FYN (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL735494 0.79 FYN (0.41) L3MBTL3L3MBTL1FYNMBTD1HTR6
SCHEMBL19312789 0.78 HTR6 (0.41) L3MBTL3L3MBTL1MBTD1HTR6TP53BP1
SCHEMBL23581363 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382240-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP Bridgestone Corporation (JP) 2011-11-02 EP disclosed
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed
WO-2010085622-A9 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-12-23 WO disclosed
WO-2010085622-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-07-29 WO disclosed