Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16942511 | 0.81 | BRD9 (0.40) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL1047342 | 0.76 | BRD9 (0.39) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL22290086 | 0.76 | BRD9 (0.36) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL29518567 | 0.76 | BRD9 (0.36) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL14771290 | 0.75 | ALDH1A1 (0.47) | MAPTKDM4ENPSR1ALDH1A1 | |
| SCHEMBL13752828 | 0.75 | BRD4 (0.38) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL14771224 | 0.74 | KDM4E (0.40) | MAPTKDM4ENPSR1ALDH1A1 | |
| SCHEMBL3570930 | 0.74 | RXFP1 (0.35) | RXFP1MAPTCYP2A6PIK3CB | |
| SCHEMBL29942174 | 0.74 | RXFP1 (0.35) | RXFP1MAPTCYP2A6PIK3CB | |
| SCHEMBL22290024 | 0.74 | BRD9 (0.36) | BRD9BRD4TAF1BRPF1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384776-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20220098190-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2022-03-31 | — | — | US | disclosed |
| EP-3917529-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098190-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | BRD9 290/4885BRD4 42/4885TAF1 293/4885 |
| US-12384776-B2 | Compounds and uses thereof | VHL, TFEB, BECN1 | BRD9 290/4885BRD4 42/4885TAF1 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.