Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.51 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173313 | 1.00 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL31173169 | 0.88 | SMARCA2 (0.50) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL22290278 | 0.88 | SMARCA2 (0.50) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL22290392 | 0.86 | MEN1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2AABL1 | |
| SCHEMBL31173274 | 0.86 | MEN1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2AABL1 | |
| SCHEMBL31173279 | 0.84 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL22290286 | 0.84 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL22971686 | 0.83 | MEN1 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2AABL1 | |
| SCHEMBL22290309 | 0.82 | SMARCA2 (0.56) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL22290753 | 0.82 | SMARCA2 (0.58) | SMARCA2SMARCA4CYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917527-B1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-16 | — | — | US | disclosed |
| EP-3917527-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| CN-113645971-A | Compound and use thereof | 福宏治疗公司 | 2021-11-12 | — | — | CN | disclosed |
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | SMARCA2 14/4885SMARCA4 6/4885CYP3A4 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.