Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.50 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290278 | 1.00 | SMARCA2 (0.50) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL22305784 | 0.89 | RAB9A (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL22290484 | 0.88 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL31173313 | 0.88 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL31173245 | 0.86 | TRPA1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL22290429 | 0.86 | TRPA1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL22290286 | 0.85 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL31173279 | 0.85 | SMARCA2 (0.51) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL22290309 | 0.82 | SMARCA2 (0.56) | SMARCA2SMARCA4CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL22290365 | 0.82 | MAPT (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645971-B | Compounds and uses thereof | 福宏治疗公司 | 2024-10-18 | — | — | CN | disclosed |