Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517344 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL2227307 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL12517342 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL2227907 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL12517341 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL2228416 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL12517664 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL2229506 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL12517668 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL12443374 | 0.70 | ALDH1A1 (0.74) | KDM4EALDH1A1L3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |