Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705826 | 0.79 | HRH1 (0.44) | HRH3HTR2ACYP1A2CYP2D6HTR1A | |
| SCHEMBL4140258 | 0.76 | CCR1 (0.41) | HRH3CYP1A2CYP2D6CYSLTR1NPC1 | |
| SCHEMBL23525243 | 0.76 | HRH3 (0.37) | HRH3HTR2AHTR2CKCNH2CYP1A2 | |
| SCHEMBL5109146 | 0.76 | HRH3 (0.44) | HRH3CYP1A2CYP2D6RXRANPC1 | |
| SCHEMBL3864978 | 0.75 | PPARG (0.38) | HRH3HTR2CCYP1A2CYP2D6RXRA | |
| SCHEMBL2717171 | 0.75 | HRH3 (0.34) | HRH3HTR2AHTR2CKCNH2CYP1A2 | |
| SCHEMBL1829134 | 0.75 | ABAT (0.34) | HRH3CYSLTR1 | |
| SCHEMBL28230882 | 0.71 | HRH3 (0.34) | HRH3HTR2AHTR2CKCNH2CYP1A2 | |
| SCHEMBL16682705 | 0.71 | RECQL (0.36) | HRH3CYP1A2CYP2D6CYSLTR1HTR1A | |
| SCHEMBL2643146 | 0.71 | PRSS1 (0.34) | HRH3CYP1A2CYP2D6CYSLTR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |