SCHEMBL222945

SCHEMBL222945

COc1cnccc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31576017 1.00
Hydrochloric Acid SCHEMBL29374919 0.98 CA12 (0.47)
SCHEMBL29536540 0.82
SCHEMBL934648 0.82
SCHEMBL9853810 0.81 PTGS1 (0.54)
SCHEMBL9853591 0.79 IDO1 (0.54)
SCHEMBL2538708 0.78 CA12 (0.53)
SCHEMBL11628534 0.77 ALDH1A1 (0.53)
SCHEMBL32667134 0.77 GAA (0.42)
SCHEMBL25567193 0.77 GAA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507243-B1 SPIROINDOLINONE PYRROLIDINES HOFFMANN LA ROCHE (CH) 2015-06-10 EP claimed
EP-2507243-A1 SPIROINDOLINONE PYRROLIDINES F. Hoffmann-La Roche AG (CH) 2012-10-10 EP claimed
CN-100340560-C N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2007-10-03 CN claimed
CN-100340558-C N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2007-10-03 CN claimed
CN-1785998-A N,N-dipyridyl 3,4,9,10-tetraformyl diimine derirative and its synthesis method UNIV DONGNAN (CN) 2006-06-14 CN claimed
CN-1763041-A N,N'-dipyridyl-equibenzyl-tetraformyldiimine derivative and its synthesis method UNIV SOUTHEAST (CN) 2006-04-26 CN claimed
EP-1412578-B1 DYED AND/OR PRINTED NON-WOVEN FABRIC FREUDENBERG CARL KG (DE) 2006-01-04 EP claimed
EP-1412578-A1 DYED AND/OR PRINTED NON-WOVEN FABRIC Carl Freudenberg KG (DE) 2004-04-28 EP claimed
EP-1086106-B1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE DARWIN DISCOVERY LTD (GB) 2003-08-20 EP claimed
WO-2003014464-A1 DYED AND/OR PRINTED NON-WOVEN FABRIC CARL FREUDENBERG KG (DE) 2003-02-20 WO claimed
WO-2002072025-A2 IMPROVING POSTSYNAPTIC RESPONSE BY A COMBINATION OF 4-MINOPYRIDINE AND AGONIST THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) 2002-09-19 WO claimed
EP-1086106-A1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE Darwin Discovery Limited (GB) 2001-03-28 EP claimed
US-6169090-B1 FOR INHIBITION OF PHOSPHODIESTERASE IV DARWIN DISCOVERY, LTD. (GB) 2001-01-02 US claimed
WO-1999064423-A1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE DARWIN DISCOVERY LIMITED (GB) 1999-12-16 WO claimed
EP-4727647-A1 GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF The Broad Institute Inc. (US) 2026-04-22 EP disclosed
US-20260103465-A1 GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2026-04-16 US disclosed
EP-4725493-A2 POLYCYCLIC COMPOUNDS FOR INHIBITING RNA HELICASE DHX33 AND USE THEREOF Shenzhen Keye Life Technologies, Co., Ltd. (CN) 2026-04-15 EP disclosed
US-5652363-A TREATING PLATELET ACTIVATING FACTOR MEDIATED DISEASES C.D. SEARLE & CO. (US) 1997-07-29 US disclosed
EP-0719257-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007892-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed