Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227778 | 0.93 | TSHR (0.37) | TSHRTHRBGBA1 | |
| SCHEMBL2227447 | 0.86 | THRB (0.38) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL18112242 | 0.77 | CYP2C19 (0.40) | TSHRALDH1A1 | |
| SCHEMBL1707503 | 0.77 | TSHR (0.45) | TSHRGBA1ALDH1A1TDP1 | |
| SCHEMBL11139184 | 0.75 | TSHR (0.43) | TSHRGBA1ALDH1A1TDP1 | |
| SCHEMBL11140684 | 0.75 | TSHR (0.43) | TSHRGBA1ALDH1A1TDP1 | |
| SCHEMBL8851279 | 0.73 | — | — | |
| SCHEMBL7373406 | 0.72 | — | — | |
| SCHEMBL6542362 | 0.71 | TSHR (0.62) | TSHRGBA1ALDH1A1TDP1 | |
| SCHEMBL2004390 | 0.70 | TSHR (0.52) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |