Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26396812 | 0.72 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL14083906 | 0.72 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL8164081 | 0.72 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL17888356 | 0.72 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL17001735 | 0.71 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL22296394 | 0.71 | HRH3 (0.40) | HRH3 | |
| SCHEMBL20065975 | 0.70 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL24859530 | 0.68 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL22313613 | 0.68 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL28329281 | 0.68 | HRH3 (0.44) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689871-A1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |