Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25778997 | 0.82 | HRH3 (0.36) | HRH3KCNH2 | |
| SCHEMBL26396812 | 0.76 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL17888356 | 0.76 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL8164081 | 0.76 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL14083906 | 0.76 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL20065975 | 0.74 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL28329281 | 0.73 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL22313613 | 0.73 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL16064390 | 0.73 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL23109012 | 0.70 | HRH3 (0.41) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548890-B1 | HPK1 antagonists and uses thereof | Nimbus Saturn, Inc. (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548890-B1 | HPK1 antagonists and uses thereof | PDXK, HIPK1, PCK1 | HRH3 387/4885KCNH2 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.