Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21369190 | 0.68 | HDAC4 (0.40) | HDAC4OPRD1OPRK1GRIN2B | |
| SCHEMBL22296289 | 0.67 | MAPK1 (0.35) | — | |
| SCHEMBL21662864 | 0.61 | DPP4 (0.32) | — | |
| SCHEMBL13328185 | 0.61 | — | — | |
| SCHEMBL4589388 | 0.58 | HDAC4 (0.59) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| O-Xylene SCHEMBL10939159 | 0.58 | TSHR (0.67) | — | |
| SCHEMBL1311200 | 0.57 | GRIN2B (0.50) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL29273456 | 0.57 | OPRM1 (0.47) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL23807015 | 0.57 | — | — | |
| SCHEMBL2338131 | 0.57 | HDAC4 (0.57) | HDAC4OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305790-B1 | METHOD FOR PREPARING IMIDAZOLE DERIVATIVE AND INTERMEDIATE THEREOF AND CRYSTAL FORM | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2020-08-05 | — | — | EP | disclosed |