Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20437948 | 0.71 | CYP2D6 (0.53) | MAPK1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL23591435 | 0.70 | BACE1 (0.44) | MAPK1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL16812445 | 0.69 | MAPK1 (0.46) | MAPK1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL22296290 | 0.67 | HDAC4 (0.37) | — | |
| SCHEMBL7004720 | 0.66 | PDE7A (0.46) | MAPK1HTR2ABACE1ALDH1A1 | |
| SCHEMBL16812427 | 0.63 | BACE1 (0.45) | MAPK1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL844744 | 0.61 | PDK2 (0.57) | LMNA | |
| SCHEMBL30242138 | 0.61 | PDK2 (0.57) | LMNA | |
| SCHEMBL31623092 | 0.61 | OPRK1 (0.50) | HTR1AHTR2AHTR7HTR6BACE1 | |
| SCHEMBL17187660 | 0.61 | BACE1 (0.50) | MAPK1HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305790-B1 | METHOD FOR PREPARING IMIDAZOLE DERIVATIVE AND INTERMEDIATE THEREOF AND CRYSTAL FORM | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2020-08-05 | — | — | EP | disclosed |