Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597686 | 0.85 | MEN1 (0.54) | KMT2ACYP1A2GRM1MAPTMEN1 | |
| SCHEMBL19243071 | 0.81 | KMT2A (0.75) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL14137820 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL13029622 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2ACYP1A2GRM1MAPT | |
| SCHEMBL13870800 | 0.78 | KMT2A (0.47) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL8353234 | 0.76 | GRM1 (0.44) | ALDH1A1NPSR1CYP1A2GRM1MAPT | |
| SCHEMBL862486 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL9755328 | 0.74 | CYP1A2 (0.65) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL29660577 | 0.74 | CYP1A2 (0.65) | ALDH1A1KMT2ANPSR1CYP1A2MAPT | |
| SCHEMBL17942819 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KMT2ANPSR1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426032-B1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-05 | — | — | EP | disclosed |