SCHEMBL13029622

SCHEMBL13029622

CCc1cc2ccccc2nc1C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
HPGD P15428 2/20 0.55
STAT3 P40763 2/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 1/20 0.55
CYP1A2 P05177 1/20 0.54
GRM1 Q13255 4/20 0.54
TLR8 Q9NR97 2/20 0.49
GLA P06280 1/20 0.48
MAPT P10636 1/20 0.48
ACHE P22303 1/20 0.48
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8645151 0.82 STAT3 (0.53) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL28160291 0.82 STAT3 (0.53) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL3641269 0.82 STAT3 (0.53) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL3633495 0.82 ALDH1A1 (0.58) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL3640530 0.82 KMT2A (0.65) ALDH1A1HPGDSTAT3KDM4EGAA
Hydrochloric Acid SCHEMBL6991460 0.81 KMT2A (0.62) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL24597657 0.80 KDM4E (0.67) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL12014829 0.80 PSMB5 (0.62) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL20043088 0.79 STAT3 (0.50) ALDH1A1HPGDSTAT3KDM4EGAA
SCHEMBL13227169 0.79 SMN1; SMN2 (0.55) ALDH1A1HPGDSTAT3KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128371-A A kind of phenthazine benzaldehyde derivative and preparation method thereof, phenthazine quinoline fluorescence probe and its preparation method and application 中国科学院上海微系统与信息技术研究所 2019-08-16 CN claimed
CN-120058625-A Organic compound and application thereof in electronic device 浙江光昊光电科技有限公司 2025-05-30 CN disclosed
CN-120058533-A Organic compound and application thereof in organic electronic device 浙江光昊光电科技有限公司 2025-05-30 CN disclosed
CN-119552184-A Organic compound, mixture, composition, organic light-emitting device and display panel TCL华星光电技术有限公司 2025-03-04 CN disclosed
CN-119409716-A Organic compound, organic light-emitting device and display panel 广州华睿光电材料有限公司 2025-02-11 CN disclosed
CN-119390718-A Organic compound, organic light-emitting device and display panel 广州华睿光电材料有限公司 2025-02-07 CN disclosed
CN-119039331-A Organic compound, mixture, composition, organic light-emitting device and display panel 广州华睿光电材料有限公司 2024-11-29 CN disclosed
CN-117693278-A Composition, mixture, light-emitting element and display panel 深圳市华星光电半导体显示技术有限公司 2024-03-12 CN disclosed
CN-117466755-A Organic compound, composition, organic electroluminescent device and display panel 深圳市华星光电半导体显示技术有限公司 2024-01-30 CN disclosed
US-11806409-B2 Imaging methods using 18F-radiolabeled biologics BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-07 US disclosed
US-20230241258-A1 IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS BRISTOL-MYERS SQUIBB COMPANY 2023-08-03 US disclosed
CN-111278834-B Aromatic amine compound, polymer, composition and organic electronic device 广州华睿光电材料有限公司 2023-04-18 CN disclosed
CN-110128371-A A kind of phenthazine benzaldehyde derivative and preparation method thereof, phenthazine quinoline fluorescence probe and its preparation method and application 中国科学院上海微系统与信息技术研究所 2019-08-16 CN disclosed
US-20170258948-A1 NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING BRISTOL-MYERS SQUIBB COMPANY 2017-09-14 US disclosed
US-8765757-B2 3-heterocyclic substituted indole derivatives and methods of use thereof MERCK SHARP & DOHME CORP. (US) 2014-07-01 US disclosed
EP-2261226-A1 Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase MILLENNIUM PHARMACEUTICALS, INC. (US) 2010-12-15 EP disclosed
EP-1485707-B1 CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS CAPROTEC BIOANALYTICS GMBH (DE) 2009-01-14 EP disclosed
US-20070015758-A1 Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors DR. REDDY'S LABORATORIES LTD. (IN) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241258-A1 IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS FCGRT, FAP, FUCA1 ALDH1A1 1702/4885HPGD 209/4885STAT3 2618/4885
US-11806409-B2 Imaging methods using 18F-radiolabeled biologics FCGRT, FAP, FUCA1 ALDH1A1 1702/4885HPGD 209/4885STAT3 2618/4885
US-20070015758-A1 Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors CETP, NPC1, DBI ALDH1A1 3986/4885HPGD 3328/4885STAT3 4632/4885
US-20170258948-A1 NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING PDCD10, PDCD1LG2, CD274 ALDH1A1 4371/4885HPGD 4222/4885STAT3 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.