Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 14/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296218 | 1.00 | JAK3 (0.47) | JAK3JAK1BTKEGFRLCK | |
| SCHEMBL22296381 | 0.86 | JAK3 (0.46) | JAK3JAK1BTKEGFR | |
| SCHEMBL22296379 | 0.84 | JAK3 (0.51) | JAK3JAK1BTKEGFR | |
| SCHEMBL22296219 | 0.84 | JAK3 (0.51) | JAK3JAK1BTKEGFR | |
| SCHEMBL22296385 | 0.84 | JAK3 (0.51) | JAK3JAK1BTKEGFR | |
| SCHEMBL22222618 | 0.82 | JAK3 (0.43) | JAK3JAK1BTKEGFR | |
| SCHEMBL22222619 | 0.82 | JAK3 (0.43) | JAK3JAK1BTKEGFRLCK | |
| SCHEMBL21706919 | 0.82 | JAK3 (0.43) | JAK3JAK1BTKEGFRLCK | |
| SCHEMBL20322723 | 0.81 | JAK3 (0.40) | JAK3JAK1BTK | |
| SCHEMBL23328302 | 0.80 | JAK3 (0.42) | JAK3JAK1BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689871-B1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3689871-A1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |