Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4807761 | 1.00 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL8009950 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL8421151 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL9013971 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL7983250 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL10525004 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL10379498 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15103409 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15666483 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL7996596 | 0.95 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3264 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080091-A | Polyacid-based photoelectric functional material with reverse-light-conduction programmable switching characteristic, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122060000-A | Bimetallic heteronuclear complex and preparation method and application thereof | 武汉光化学技术研究院 | 2026-05-19 | — | — | CN | claimed |
| CN-122063209-A | Method for detecting hexavalent chromium in soil and sediment | 中煤浙江检测技术有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122042355-A | Pretreatment and detection method for measuring content of polycyclic aromatic hydrocarbon in biochar-based fertilizer | 江苏省农产品质量检验测试中心 | 2026-05-15 | — | — | CN | claimed |
| CN-122017222-A | Application of improved isoluminol luminous substrate in MaglumiX chemiluminescent immunoassay system | 浙江鑫科医疗科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-115881873-B | High-light-transmittance low-moisture-absorption material for LED packaging and preparation method thereof | 齐鲁工业大学(山东省科学院) | 2026-05-12 | — | — | CN | claimed |
| CN-115896050-B | 7 Alpha-hydroxysteroid dehydrogenase terminal modification combining point mutation and efficient synthesis of ursodeoxycholic acid intermediate | 江南大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120121609-A | Safe and stable oxygen indicator and preparation method thereof | 淮安市威特保鲜剂有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120121750-A | Liquid chromatography tandem mass spectrometry detection method for catecholamine and metabolite thereof | 上海拜谱生物科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120041096-A | High-transparency long-acting antistatic dustproof coating and preparation method thereof | 湖南大学 | 2025-05-27 | — | — | CN | claimed |
| CN-1072588-A | Hair nourishing agent and production method thereof | TANISAKE KK (JP) | 1993-06-02 | — | — | CN | claimed |
| US-4935230-A | THIOGLYCERYL ETHER OR 1-PHENYL-2-MERCAPTOETHANOL | KAO CORPORATION (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0129807-A2 | Hair treatment composition for heat waving and method for waving hair | Kao Corporation (JP) | 1985-01-02 | — | — | EP | claimed |
| US-4368134-A | HEAVY DUTY LAUNDRY DETERGENTS | COLGATE PALMOLIVE COMPANY (US) | 1983-01-11 | — | — | US | claimed |
| US-4362640-A | Method for retarding gelation of crutcher slurries containing bicarbonate, carbonate and silicate | COLGATE-PALMOLIVE COMPANY (US) | 1982-12-07 | — | — | US | claimed |
| US-4311607-A | Method for manufacture of non-gelling, stable zeolite - inorganic salt crutcher slurries | COLGATE PALMOLIVE COMPANY (US) | 1982-01-19 | — | — | US | claimed |
| US-4311606-A | Method for manufacture of non-gelling, stable inorganic salt crutcher slurries | COLGATE PALMOLIVE COMPANY (US) | 1982-01-19 | — | — | US | claimed |
| US-4298493-A | CITRIC ACID OR WATER SOLUBLE CITRATE | COLGATE-PALMOLIVE COMPANY (US) | 1981-11-03 | — | — | US | claimed |
| US-4294718-A | SODIUM CARBONATE-BICARBONATE-SILICATE, CITRIC ACID OR SALT AND MAGNESIUM SULFATE | COLGATE-PALMOLIVE COMPANY (US) | 1981-10-13 | — | — | US | claimed |
| US-4238420-A | Production of hexanitrostilbene using inorganic buffers | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1980-12-09 | — | — | US | claimed |