Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LDLR | P01130 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299445 | 0.86 | NPC1 (0.46) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL31576865 | 0.86 | NPC1 (0.46) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL22299219 | 0.86 | MAPT (0.47) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL31576995 | 0.86 | AAK1 (0.47) | AAK1ALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL31576864 | 0.86 | MAPT (0.47) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL22288564 | 0.86 | AAK1 (0.47) | AAK1ALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL31577159 | 0.80 | RORC (0.49) | AAK1NPC1RAB9ATDP1MEN1 | |
| SCHEMBL31577151 | 0.78 | KCNQ2 (0.65) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL22298751 | 0.78 | KCNQ2 (0.65) | ALDH1A1NPC1HPGDRAB9ANFKB1 | |
| SCHEMBL31577177 | 0.78 | HDAC3 (0.51) | MCHR1KCNQ3KCNQ2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | claimed |
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |