Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299561 | 0.86 | SRC (0.52) | SRCPTPN1TYRBCHEACHE | |
| SCHEMBL29571282 | 0.81 | SRC (1.00) | SRCPTPN1ALDH1A1GSK3B | |
| SCHEMBL16749882 | 0.81 | SRC (1.00) | SRCPTPN1ALDH1A1GSK3B | |
| SCHEMBL16749879 | 0.81 | SRC (1.00) | SRCPTPN1ALDH1A1GSK3B | |
| SCHEMBL31545696 | 0.81 | SRC (1.00) | SRCPTPN1ALDH1A1GSK3B | |
| SCHEMBL29412614 | 0.81 | SRC (1.00) | SRCPTPN1ALDH1A1GSK3B | |
| SCHEMBL22299950 | 0.80 | SRC (0.56) | SRCPTPN1BCHEACHEGSK3B | |
| SCHEMBL24278908 | 0.79 | SRC (0.71) | SRCPTPN1PPARGPPARAALDH1A1 | |
| SCHEMBL31545802 | 0.78 | SRC (0.69) | SRCPTPN1PPARGALDH1A1CYP3A4 | |
| SCHEMBL11961096 | 0.77 | TYR (0.59) | TYRBCHEACHETRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105051-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2022-04-07 | — | — | US | disclosed |
| WO-2020154811-A9 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020154811-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105051-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | HDAC1, TAP1, HDAC11 | SRC 2561/4885PTPN1 2769/4885TYR 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.