Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MSR1 | P21757 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31545696 | 1.00 | SRC (1.00) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL29412614 | 1.00 | SRC (1.00) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL29571282 | 1.00 | SRC (1.00) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL16749879 | 1.00 | SRC (1.00) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL31545340 | 0.88 | SRC (0.78) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL29966905 | 0.88 | SRC (0.78) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL16749880 | 0.84 | SRC (0.73) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL24278908 | 0.83 | SRC (0.71) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL31545802 | 0.82 | SRC (0.69) | SRCPTPN1TRPA1LMNACHRM1 | |
| SCHEMBL22299552 | 0.81 | SRC (0.68) | SRCPTPN1ALDH1A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841109-B1 | PRODRUGS OF HYDROXYL-COMPRISING DRUGS | ASCENDIS PHARMA AS (DK) | 2026-04-15 | — | — | EP | disclosed |
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | ASCENDIS PHARMA A/S (DK) | 2023-04-20 | — | — | US | disclosed |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | ASCENDIS PHARMA A/S (DE) | 2023-01-24 | — | — | US | disclosed |
| EP-4011396-A1 | RELEASABLE CONJUGATES | QuiaPEG Pharmaceuticals AB (SE) | 2022-06-15 | — | — | EP | disclosed |
| US-20220105051-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2022-04-07 | — | — | US | disclosed |
| US-20220105051-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2022-04-07 | — | — | US | disclosed |
| US-20220062195-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | Cava Healthcare Inc. (CA) | 2022-03-03 | — | — | US | disclosed |
| US-11197832-B2 | Curcuphenol compounds for increasing MHC-I expression | Cava Healthcare Inc. (CA) | 2021-12-14 | — | — | US | disclosed |
| US-20200375917-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | BIOMMUNE TECHNOLOGIES INC. (CA) | 2020-12-03 | — | — | US | disclosed |
| WO-2020154811-A9 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2020-09-17 | — | — | WO | disclosed |
| US-10751296-B2 | Curcuphenol compounds for increasing MHC-I expression | Cava Healthcare Inc. (CA) | 2020-08-25 | — | — | US | disclosed |
| WO-2020154811-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | Cava Healthcare Inc. (CA) | 2020-08-06 | — | — | WO | disclosed |
| US-20170319508-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | Cava Healthcare Inc. (CA) | 2017-11-09 | — | — | US | disclosed |
| US-20170319508-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | Cava Healthcare Inc. (CA) | 2017-11-09 | — | — | US | disclosed |
| US-20150147314-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | JEFFERIES, WILFRED (CA) | 2015-05-28 | — | — | US | disclosed |
| US-20150147314-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | JEFFERIES, WILFRED (CA) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319508-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-10751296-B2 | Curcuphenol compounds for increasing MHC-I expression | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-20220062195-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | PLG, PHYKPL, PLOD3 | SRC 1526/4885PTPN1 2002/4885TRPA1 4725/4885 |
| US-20220105051-A1 | COMPOUNDS FOR INCREASING MHC-I EXPRESSION AND MODULATING HISTONE DEACETYLASE ACTIVITY | HDAC1, TAP1, HDAC11 | SRC 2561/4885PTPN1 2769/4885TRPA1 407/4885 |
| US-11197832-B2 | Curcuphenol compounds for increasing MHC-I expression | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-20200375917-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | SRC 2234/4885PTPN1 3492/4885TRPA1 4884/4885 |
| US-20150147314-A1 | CURCUPHENOL COMPOUNDS FOR INCREASING MHC-I EXPRESSION | CD74, MICA, HLA-DRB1 | SRC 2209/4885PTPN1 2945/4885TRPA1 190/4885 |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | PLG, PHYKPL, PLOD3 | SRC 1526/4885PTPN1 2002/4885TRPA1 4725/4885 |
| US-11786599-B2 | Releasable conjugates | GUSB, ABCB11, UGT2B7 | SRC 2234/4885PTPN1 3492/4885TRPA1 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.