Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.72 |
| ▸ | EGFR | P00533 | 8/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299722 | 0.88 | HTT (0.74) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6181626 | 0.85 | MEN1 (1.00) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22164645 | 0.85 | HTT (0.81) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL22290778 | 0.84 | EGFR (0.80) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL31429504 | 0.84 | EGFR (0.80) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13192098 | 0.84 | EGFR (0.97) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6179448 | 0.84 | EGFR (1.00) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22169931 | 0.83 | HTT (0.74) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22299727 | 0.83 | EGFR (0.76) | EGFRLCK | |
| SCHEMBL22290998 | 0.81 | HTT (0.71) | HTTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160333-A1 | ENPP1 INHIBITORS AND METHODS OF MODULATING IMMUNE RESPONSE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |