Naphthalene

Naphthalene

SCHEMBL2230173

CCCCCCC1Cc2ccccc2N1.c1ccc2ccccc2c1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PRKCD Q05655 4/20 0.44
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
BRD4 O60885 1/20 0.37
CREBBP Q92793 1/20 0.37
MTNR1A P48039 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
S1PR2 O95136 1/20 0.33
S1PR4 O95977 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
S1PR5 Q9H228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL7009617 1.00 ALDH1A1 (0.44) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7006954 0.98 ALDH1A1 (0.45) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL23010557 0.95 ALDH1A1 (0.47) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL28923894 0.95 ALDH1A1 (0.47) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7011468 0.94 ALDH1A1 (0.40) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL19987645 0.94 ALDH1A1 (0.48) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL9079542 0.90 PRKCD (0.38) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL28923868 0.89 ALDH1A1 (0.43) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7004559 0.88 CREBBP (0.41) PRKCDBRD4CREBBPMTNR1AGAA
SCHEMBL10924393 0.86 PRKCD (0.40) ALDH1A1MEN1KMT2APRKCDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130494-A ESTER, AMINE PHOSPHATE SALT EXXON RESEARCH & ENGINEERING CO. (US) 1978-12-19 US claimed
US-20170130161-A1 COMPRESSOR OIL WITH BIOBASED BASE OIL NOVVI LLC 2017-05-11 US disclosed
US-20170121630-A1 HYDRAULIC FLUIDS FROM RENEWABLE ISOPARAFFINS NOVVI LLC 2017-05-04 US disclosed
EP-1100856-B1 DIESEL ENGINE CYLINDER OILS EXXONMOBIL OIL CORP (US) 2016-02-17 EP disclosed
EP-1121404-B1 HIGH PERFORMANCE LUBRICATING OILS EXXONMOBIL OIL CORP (US) 2016-02-03 EP disclosed
EP-2021440-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2015-07-01 EP disclosed
US-8476205-B2 Chromium HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-07-02 US disclosed
US-8399390-B2 HVI-PAO in industrial lubricant and grease compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-19 US disclosed
US-8273694-B2 Synthetic compositions obtained from algae Brown, Jeffrey A (US) 2012-09-25 US disclosed
US-8247358-B2 HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-08-21 US disclosed
US-5486300-A Lubricating compositions THE LUBRIZOL CORPORATION (US) 1996-01-23 US disclosed
EP-0678569-A2 Lubricating compositions with improved oxidation resistance containing a dispersant and an antioxidant THE LUBRIZOL CORPORATION (US) 1995-10-25 EP disclosed
EP-0471071-B1 HIGH TEMPERATURE FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 1995-08-30 EP disclosed
US-5366648-A Functional fluids useful at high temperatures THE LUBRIZOL CORPORATION (US) 1994-11-22 US disclosed
EP-0535221-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
EP-0535217-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
WO-1992018588-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
WO-1992018589-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
EP-0471071-A1 HIGH TEMPERATURE FUNCTIONAL FLUIDS. LUBRIZOL CORP (US) 1992-02-19 EP disclosed
WO-1991013133-A2 HIGH TEMPERATURE FUNCTIONAL FLUIDS THE LUBRIZOL CORPORATION (US) 1991-09-05 WO disclosed