Naphthalene

Naphthalene

SCHEMBL7006954

CCCCCC1Cc2ccccc2N1.c1ccc2ccccc2c1

nearest known ligand 0.45

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
PRKCD Q05655 4/20 0.42
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
BRD4 O60885 2/20 0.38
CREBBP Q92793 2/20 0.38
MTNR1A P48039 3/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL2230173 0.98 ALDH1A1 (0.44) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7009617 0.98 ALDH1A1 (0.44) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7011468 0.95 ALDH1A1 (0.40) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL19987645 0.95 ALDH1A1 (0.48) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL23010557 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL28923894 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL28923868 0.91 ALDH1A1 (0.43) ALDH1A1MEN1KMT2APRKCDL3MBTL1
Naphthalene SCHEMBL7004559 0.89 CREBBP (0.41) PRKCDBRD4CREBBPMTNR1AGAA
Naphthalene SCHEMBL9079542 0.89 PRKCD (0.38) ALDH1A1MEN1KMT2APRKCDL3MBTL1
SCHEMBL11333479 0.85 MEN1 (0.40) ALDH1A1MEN1KMT2APRKCDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
EP-0860495-B1 Lubricating oil composition TONEN CORP (JP) 2003-01-08 EP disclosed
US-6147035-A DETERGENCY; HEAT AND OXIDATION RESISTANCE; REDUCE NITROGEN OXIDE EMISSION TONEN CORPORATION (JP) 2000-11-14 US disclosed
EP-0719853-B1 Fluid composition for use in fluid coupling TONEN CORP (JP) 2000-09-20 EP disclosed
EP-0839175-A4 LUBRICATING OIL COMPOSITION EXXON RESEARCH ENGINEERING CO (US) 1999-06-23 EP disclosed
US-5880073-A BASE OIL OF SPECIFIED COMPOSITION CONTAINING DIARYLAMINE COMPOUND AND OXYMOLYBDENUM SULFIDE DITHIOXANTHOGENATE COMPOUND TONEN CORPORATION (JP) 1999-03-09 US disclosed
EP-0860495-A2 Lubricating oil composition TONEN CORPORATION (JP) 1998-08-26 EP disclosed
EP-0839175-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-05-06 EP disclosed
US-5747429-A SILICONE OIL TONEN CORPORATION (JP) 1998-05-05 US disclosed
WO-1996037583-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1996-11-28 WO disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed