Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 10/20 | 0.33 |
| ▸ | PKM | P14618 | 5/20 | 0.33 |
| ▸ | PKLR | P30613 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289905 | 0.81 | BRD4 (0.40) | BRD9BRD4MAPTGPR35KDM4E | |
| SCHEMBL15716610 | 0.80 | BRD9 (0.32) | BRD9BRD7BRD4PKMPKLR | |
| SCHEMBL28646175 | 0.80 | BRD4 (0.42) | BRD9BRD4 | |
| SCHEMBL15728258 | 0.79 | PKM (0.32) | PKM | |
| SCHEMBL15716772 | 0.79 | GSK3B (0.31) | — | |
| SCHEMBL15716758 | 0.78 | PKM (0.33) | BRD9BRD4PKMPKLRL3MBTL1 | |
| SCHEMBL19747304 | 0.78 | PKM (0.34) | BRD9BRD4PKMPKLRKDM4E | |
| SCHEMBL22289951 | 0.77 | BRD4 (0.46) | BRD9BRD4PKMMAPTNPSR1 | |
| SCHEMBL21904793 | 0.77 | TSHR (0.57) | BRD9BRD4PKMRAB9AMAPT | |
| SCHEMBL15716896 | 0.75 | CA2 (0.35) | BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155100-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2020160193-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |