Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RGS8 | P57771 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17928363 | 0.84 | CYP3A4 (0.57) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL22442062 | 0.84 | APEX1 (0.42) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL22442061 | 0.84 | APEX1 (0.42) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL26454766 | 0.81 | RGS4 (0.32) | RGS4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26455386 | 0.81 | RGS4 (0.31) | RGS4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10000321 | 0.79 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8764940 | 0.78 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL961942 | 0.78 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL25260229 | 0.76 | RGS4 (0.35) | RGS4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26454539 | 0.75 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674936-A | ROOM TEMPERATURE VULCANIZABLE; AN ALKYLALKOXY END-STOPPED DIORGANOPOLYSILOXANE. A POLYALKOXYSILANE CROSSLINKING AGENT, A TETRAALKYL TITANATE CURING CATALYST AND 1,3,5-TRIS(ALKOXYSILYLALKYL)ISOCYANURATE | GENERAL ELECTRIC COMPANY (US) | 1997-10-07 | — | — | US | claimed |
| EP-1954702-B1 | RADIATION CURE SILICONE COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2016-09-28 | — | — | EP | disclosed |
| US-20150291839-A1 | Moisture-Curing Compositions, Methods and Products | CUSTOM BUILDING PRODUCTS, LLC | 2015-10-15 | — | — | US | disclosed |
| US-7981978-B2 | Low modulus, humidity resistant silicone RTV compositions and method of preparing same | HENKEL CORPORATION (US) | 2011-07-19 | — | — | US | disclosed |
| US-20100139843-A1 | LOW MODULUS, HUMIDITY RESISTANT SILICONE RTV COMPOSITIONS AND METHOD OF PREPARING SAME | HENKEL CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| US-7674871-B2 | quaternized terminated polydimethylsiloxane; sealant; activating by irradiation | HENKEL AG & CO. KGAA (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20080306208-A1 | Rapid Surface Curing Silicone Compositions | HENKEL CORPORATION (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080268161-A1 | Radiation Cure Silicone Compositions | HENKEL CORPORATION (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080064815-A1 | Reinforcement and Cure Enhancement of Curable Resins | HENKEL CORPORATION | 2008-03-13 | — | — | US | disclosed |
| US-20070043194-A1 | Fast curing polydiorganosiloxanes | HENKEL AG & CO. KGAA (DE) | 2007-02-22 | — | — | US | disclosed |
| US-20050234208-A1 | Fast curing polydiorganosiloxanes | HENKEL AG & CO. KGAA (DE) | 2005-10-20 | — | — | US | disclosed |
| EP-0449413-B1 | Polymers | ICI PLC (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5274064-A | An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | disclosed |
| EP-0449413-A1 | Polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080268161-A1 | Radiation Cure Silicone Compositions | MGMT, RAD51, SGMS1 | RGS4 3666/4885PDE4A 2730/4885PDE4B 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.