Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351591 | 0.85 | ADORA2B (0.33) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL2230205 | 0.79 | RGS4 (0.33) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL14150298 | 0.77 | TNF (0.33) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL2502693 | 0.76 | RGS4 (0.32) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL383223 | 0.74 | RGS4 (0.32) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL13089574 | 0.73 | — | — | |
| SCHEMBL8764940 | 0.72 | PDE4A (0.31) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL16411930 | 0.71 | PDE4A (0.33) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL12636929 | 0.71 | — | — | |
| SCHEMBL10000322 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124715-B2 | Isocyanuric ring-containing polysiloxane having vinyl groups at the terminals | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110105713-A1 | ISOCYANURIC RING-CONTAINING POLYSILOXANE HAVING VINYL GROUPS AT THE TERMINALS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-05-05 | — | — | US | disclosed |