Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228518 | 0.85 | CHRM4 (0.39) | CHRM4MEN1KMT2AFAAHGRIN2B | |
| SCHEMBL2231117 | 0.84 | TEAD1 (0.47) | CHRM4FAAHMMP2MMP9GRIN2B | |
| SCHEMBL2228092 | 0.84 | GRM5 (0.41) | CHRM4FAAHCTSS | |
| SCHEMBL2229435 | 0.84 | TEAD1 (0.45) | CHRM4FAAHMMP2MMP9GRIN2B | |
| SCHEMBL2227846 | 0.84 | HRH2 (0.44) | CHRM4FAAHMMP2MMP9GRIN2B | |
| SCHEMBL2227842 | 0.84 | GRIN2B (0.45) | CHRM4MEN1KMT2AFAAHMMP2 | |
| SCHEMBL2228875 | 0.82 | HRH2 (0.48) | MMP2MMP9TEAD1TEAD3HRH2 | |
| SCHEMBL2229885 | 0.81 | GPR119 (0.43) | CHRM4MMP2MMP9GRIN2B | |
| SCHEMBL2228262 | 0.80 | GRIN2B (0.48) | CHRM4FAAHGRIN2BCYP3A4CYP2D6 | |
| SCHEMBL2228993 | 0.79 | KDM4E (0.44) | CHRM4MEN1KMT2AFAAHMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |