Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230209 | 0.85 | CHRM4 (0.40) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 | |
| SCHEMBL2227842 | 0.85 | GRIN2B (0.45) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 | |
| SCHEMBL2227630 | 0.85 | TEAD1 (0.47) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 | |
| SCHEMBL2228814 | 0.85 | GRM5 (0.41) | CHRM4FAAHCTSSKMT2ARAB9A | |
| SCHEMBL2228392 | 0.84 | TEAD1 (0.45) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 | |
| SCHEMBL13837342 | 0.84 | HRH2 (0.43) | CHRM4FAAHGRIN2BFNTAFNTB | |
| SCHEMBL2228311 | 0.84 | FAAH (0.44) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 | |
| SCHEMBL2229515 | 0.82 | HRH2 (0.47) | GRIN2BFNTAFNTBPGGT1B | |
| SCHEMBL2229291 | 0.81 | GPR119 (0.41) | CHRM4GRIN2BCTSS | |
| SCHEMBL2226276 | 0.81 | TEAD1 (0.53) | CHRM4FAAHGRIN2BCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |