SCHEMBL22302452

SCHEMBL22302452

Nc1cc(C=O)c(O)cc1C=O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 10/20 0.43
TYR P14679 2/20 0.39
TRIM24 O15164 2/20 0.39
TRIM33 Q9UPN9 2/20 0.39
PIM1 P11309 1/20 0.39
CDK1 P06493 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20136047 0.88 ERN1 (0.45) ERN1TYRTRIM24TRIM33CDK1
SCHEMBL12336815 0.86 ERN1 (0.43) ERN1TYRTRIM24TRIM33CDK1
SCHEMBL4941671 0.86 PIM1 (0.39) ERN1TYRTRIM24TRIM33PIM1
SCHEMBL4289408 0.84 ERN1 (0.54) ERN1TYRTRIM24TRIM33PIM1
SCHEMBL8024070 0.84 TDP1 (0.40) ERN1TRIM24TRIM33
SCHEMBL16649287 0.80 ERN1 (0.44) ERN1TRIM24TRIM33PIM1
SCHEMBL14695048 0.79 PTK2 (0.47) ERN1
SCHEMBL441302 0.79 ERN1 (0.50) ERN1TYRTRIM24TRIM33PIM1
SCHEMBL8024078 0.76 PTK2 (0.41) ERN1TRIM24TRIM33
SCHEMBL17660183 0.76 ERN1 (0.52) ERN1TYRTRIM24TRIM33CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530288-B2 Anhydrous routes to highly processable covalent network polymers and blends MALLINDA (US) 2022-12-20 US disclosed
US-20200247937-A1 ANHYDROUS ROUTES TO HIGHLY PROCESSABLE COVALENT NETWORK POLYMERS AND BLENDS MALLINDA 2020-08-06 US disclosed