Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302452 | 0.86 | ERN1 (0.43) | PIM1TRIM24TRIM33ERN1TYR | |
| SCHEMBL8024078 | 0.82 | PTK2 (0.41) | TRIM24TRIM33ERN1KDM4EMEN1 | |
| SCHEMBL12336815 | 0.81 | ERN1 (0.43) | TRIM24TRIM33ERN1KDM4EMEN1 | |
| SCHEMBL16649287 | 0.80 | ERN1 (0.44) | PIM1TRIM24TRIM33ERN1 | |
| SCHEMBL14695048 | 0.79 | PTK2 (0.47) | ERN1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8024070 | 0.79 | TDP1 (0.40) | TRIM24TRIM33ERN1KDM4EMEN1 | |
| SCHEMBL29957578 | 0.76 | ALDH1A1 (0.52) | TRIM24TRIM33ERN1KDM4EALDH1A1 | |
| SCHEMBL27614940 | 0.76 | ALDH1A1 (0.52) | TRIM24TRIM33ERN1KDM4EALDH1A1 | |
| SCHEMBL4289408 | 0.73 | ERN1 (0.54) | PIM1TRIM24TRIM33ERN1TYR | |
| SCHEMBL28992032 | 0.73 | TRIM24 (0.50) | PIM1TRIM24TRIM33ERN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051659-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-04-26 | — | — | WO | disclosed |