Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 9/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14695048 | 0.94 | PTK2 (0.47) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL8024078 | 0.90 | PTK2 (0.41) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL22302452 | 0.84 | ERN1 (0.43) | ERN1TRIM24TRIM33 | |
| SCHEMBL8444257 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRKDM4EERN1 | |
| SCHEMBL3197190 | 0.83 | ERN1 (0.41) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL15713801 | 0.81 | ERN1 (0.40) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL2307383 | 0.81 | GAA (0.46) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL3204262 | 0.81 | TSHR (0.48) | TDP1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL24389243 | 0.79 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL29077012 | 0.79 | CA12 (0.36) | TSHRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000187-A | THERMAL STABILITY, COATINGS, CAST FILMS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1976-12-28 | — | — | US | claimed |
| EP-0444142-B1 | POLYQUINOLINE COPOLYMERS | HITACHI CHEMICAL CO LTD (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5017677-A | Molding materials, laminates, adhesives, films and fibers | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-4000187-A | THERMAL STABILITY, COATINGS, CAST FILMS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1976-12-28 | — | — | US | disclosed |