SCHEMBL2230293

SCHEMBL2230293

CCCCC(CC)CC(N)(CC(CC)CCCC)n1nnc2c(C)cccc21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.38
GRM2 Q14416 2/20 0.34
CRHR1 P34998 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
XBP1 P17861 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502087 0.82 CYP4Z1 (0.45) TLR8KDM4EALDH1A1GAAHPGD
SCHEMBL28052457 0.79 TLR8 (0.44) TLR8GRM2
SCHEMBL29924005 0.77 GRM2 (0.46) TLR8GRM2KDM4EALDH1A1GAA
SCHEMBL10756591 0.76 CYP4Z1 (0.41) TLR8KDM4EALDH1A1GAAHPGD
SCHEMBL23722806 0.74 TLR8 (0.36) TLR8GRM2KDM4EALDH1A1GAA
SCHEMBL28633712 0.74 CYP4Z1 (0.44) TLR8GRM2CRHR1KDM4EALDH1A1
SCHEMBL728570 0.73 ALDH1A1 (0.45) TLR8GRM2KDM4EALDH1A1GAA
SCHEMBL5162824 0.72 GRM2 (0.41) TLR8GRM2KDM4EALDH1A1GAA
SCHEMBL14785506 0.72 TLR8 (0.35) TLR8GRM2KDM4EALDH1A1GAA
SCHEMBL728569 0.72 GRM2 (0.41) TLR8GRM2KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114854473-B Centrifugal compressor oil additive composition and application thereof 中国石油天然气股份有限公司 2023-04-25 CN claimed
CN-114854473-A Centrifugal compressor oil additive composition and application thereof 中国石油天然气股份有限公司 2022-08-05 CN claimed
CN-114854473-B Centrifugal compressor oil additive composition and application thereof 中国石油天然气股份有限公司 2023-04-25 CN disclosed
CN-114854473-A Centrifugal compressor oil additive composition and application thereof 中国石油天然气股份有限公司 2022-08-05 CN disclosed
CN-113881480-B Centrifugal compressor oil additive composition 中国石油天然气股份有限公司 2022-07-05 CN disclosed
EP-3740545-A1 ULTRA LOW ASH LUBRICATING OIL COMPOSITIONS Chevron Oronite Company LLC (US) 2020-11-25 EP disclosed
CN-111615549-A Ultra-low ash lubricating oil composition 雪佛龙奥伦耐有限责任公司 2020-09-01 CN disclosed
WO-2020040249-A1 HEAT-RESISTANT RELEASE AGENT COMPOSITION 株式会社ネオス 2020-02-27 WO disclosed
WO-2019142059-A1 ULTRA LOW ASH LUBRICATING OIL COMPOSITIONS CHEVRON ORONITE COMPANY LLC (US) 2019-07-25 WO disclosed
EP-2344581-A1 IMPROVED HVI-PAO BI-MODAL LUBRICANT COMPOSITIONS ExxonMobil Research and Engineering Company (US) 2011-07-20 EP disclosed
US-20100173808-A1 MULTIPLE METAL CORROSION INHIBITOR CHASAN DAVID E 2010-07-08 US disclosed
WO-2010039266-A1 IMPROVED HVI-PAO BI-MODAL LUBRICANT COMPOSITIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-04-08 WO disclosed
EP-2118245-A2 MULTIPLE METAL CORROSION INHIBITOR Ciba Holding Inc. (CH) 2009-11-18 EP disclosed
US-20080200357-A1 Multiple metal corrosion inhibitor CIBA CORP. 2008-08-21 US disclosed
WO-2008095805-A2 MULTIPLE METAL CORROSION INHIBITOR CIBA HOLDING INC. (CH) 2008-08-14 WO disclosed
US-4701273-A Lubricant compositions containing antioxidants, amine phosphates and 4- (5-) methyl-1-[di-(2-ethylhexyl) aminomethyl]-benzotriazole CIBA-GEIGY CORPORATION (US) 1987-10-20 US disclosed
EP-0205398-A1 Additive for functional fluids CIBA-GEIGY AG (CH) 1986-12-17 EP disclosed