Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526884 | 0.88 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL2227826 | 0.87 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL2227832 | 0.87 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL2228515 | 0.87 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL2170234 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL2245058 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL13107014 | 0.80 | EED (0.67) | SLC6A2SLC6A4SLC6A3TDP1MAP2K1 | |
| SCHEMBL2230001 | 0.80 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL791643 | 0.79 | TDP1 (0.69) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL3443378 | 0.79 | TDP1 (0.65) | SLC6A2SLC6A4SLC6A3TDP1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000010-B2 | Alkyl-heterocycle carbamate derivatives, their preparation and their therapeutic application | SANOFI (FR) | 2015-04-07 | — | — | US | disclosed |
| EP-2526100-B1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2013-12-04 | — | — | EP | disclosed |
| US-20120295909-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2012-11-22 | — | — | US | disclosed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295909-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | PRMT9, PRMT8, CBR1 | SLC6A2 2876/4885SLC6A4 3841/4885SLC6A3 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.