Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385703 | 0.91 | ABCC3 (0.58) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5370410 | 0.91 | ABCC3 (0.58) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5369113 | 0.85 | KLK5 (0.50) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5839261 | 0.85 | ABCC3 (0.54) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5373893 | 0.82 | CYP3A4 (0.51) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL7391504 | 0.82 | ABCC3 (0.47) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL30261823 | 0.81 | ABCC3 (0.65) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5368677 | 0.81 | KLK5 (0.55) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL7152588 | 0.81 | KLK5 (0.55) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL4961238 | 0.81 | ADORA3 (0.64) | CYP3A4ABCC3ABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159343-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING MIDDLE EAST RESPIRATORY SYNDROME | 재단법인 경기도경제과학진흥원 | 2020-08-06 | — | — | WO | disclosed |