SCHEMBL2230595

SCHEMBL2230595

CC(C)([C@@H]1CCCO1)[C@H]1CCCO1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17642438 1.00 NOS2 (0.31) NOS2
SCHEMBL18419229 1.00 NOS2 (0.31) NOS2
SCHEMBL36547 1.00 NOS2 (0.31) NOS2
SCHEMBL18419228 1.00 NOS2 (0.31) NOS2
SCHEMBL15809089 1.00 NOS2 (0.31) NOS2
SCHEMBL15809090 0.92
SCHEMBL1188985 0.91
SCHEMBL30894549 0.85
SCHEMBL8062477 0.85 SMN1; SMN2 (0.36)
SCHEMBL798034 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177693-A1 METHOD OF EPOXIDATION UNIVERSITY OF DURHAM (GB) 2022-06-09 US disclosed
US-10723817-B2 Vinyl modifier composition and processes for utilizing such composition BRIDGESTONE CORPORATION (JP) 2020-07-28 US disclosed
US-10000460-B2 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst THOMAS SWAN & CO. LTD (GB) 2018-06-19 US disclosed
US-10000460-B2 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst THOMAS SWAN & CO. LTD (GB) 2018-06-19 US disclosed
US-20180134815-A1 Vinyl Modifier Composition And Processes For Utilizing Such Composition BRIDGESTONE CORPORATION (JP) 2018-05-17 US disclosed
EP-3134203-B1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST SWAN THOMAS & CO LTD (GB) 2018-04-04 EP disclosed
US-9868795-B2 Vinyl modifier composition and processes for utilizing such composition BRIDGESTONE CORPORATION (JP) 2018-01-16 US disclosed
US-9751848-B2 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst THOMAS SWAN & CO. LTD (GB) 2017-09-05 US disclosed
US-9751848-B2 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst THOMAS SWAN & CO. LTD (GB) 2017-09-05 US disclosed
US-20170197929-A1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST THOMAS SWAN & CO. LTD (GB) 2017-07-13 US disclosed
US-20170029394-A1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST THOMAS SWAN & CO. LTD (GB) 2017-02-02 US disclosed
US-20160237181-A1 Vinyl Modifier Composition And Processes For Utilizing Such Composition BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
US-9309330-B2 Vinyl modifier composition and processes for utilizing such composition BRIDGESTONE CORPORATION (JP) 2016-04-12 US disclosed
WO-2016046575-A1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST THOMAS SWAN & CO. LTD (GB) 2016-03-31 WO disclosed
US-20150284483-A1 Vinyl Modifier Composition And Processes For Utilizing Such Composition BRIDGESTONE CORPORATION (JP) 2015-10-08 US disclosed
US-9062017-B2 Vinyl modifier composition and processes for utilizing such composition BRIDGESTONE CORPORATION (JP) 2015-06-23 US disclosed
EP-2516410-B1 IMPROVED VINYL MODIFIER COMPOSITION AND PROCESSES FOR UTILIZING SUCH COMPOSITION BRIDGESTONE CORP (JP) 2014-04-23 EP disclosed
EP-2516410-A1 IMPROVED VINYL MODIFIER COMPOSITION AND PROCESSES FOR UTILIZING SUCH COMPOSITION Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20120259082-A1 VINYL MODIFIER COMPOSITION AND PROCESSES FOR UTILIZING SUCH COMPOSITION BRIDGESTONE CORPORATION (JP) 2012-10-11 US disclosed
WO-2011087841-A1 IMPROVED VINYL MODIFIER COMPOSITION AND PROCESSES FOR UTILIZING SUCH COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10000460-B2 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst CAT, CTCF, CEL NOS2 3867/4885
US-20170197929-A1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST CAT, CEL, CTCF NOS2 3194/4885
US-20120259082-A1 VINYL MODIFIER COMPOSITION AND PROCESSES FOR UTILIZING SUCH COMPOSITION VCL, MVD, VAV1 NOS2 2429/4885
US-20170029394-A1 CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST CAT, CEL, CTCF NOS2 3194/4885
US-20160237181-A1 Vinyl Modifier Composition And Processes For Utilizing Such Composition VCL, MVD, VAV1 NOS2 2960/4885
US-10723817-B2 Vinyl modifier composition and processes for utilizing such composition VCL, MVD, VAV1 NOS2 2960/4885
US-20180134815-A1 Vinyl Modifier Composition And Processes For Utilizing Such Composition VCL, MVD, VAV1 NOS2 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.