Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966743 | 1.00 | ATM (0.34) | ATMALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL22306166 | 1.00 | ATM (0.34) | ATMALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL16903332 | 0.86 | L3MBTL1 (0.33) | ATMALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL24734693 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2NCF1 | |
| SCHEMBL15314555 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2NCF1 | |
| SCHEMBL16903333 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2NCF1 | |
| SCHEMBL24811602 | 0.77 | — | — | |
| SCHEMBL18313067 | 0.75 | — | — | |
| SCHEMBL18068174 | 0.74 | — | — | |
| SCHEMBL19199012 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |