Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 8/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031276 | 0.74 | CCR1 (0.42) | CCR1CCR5CCR8PARP1 | |
| SCHEMBL22306189 | 0.74 | F2RL3 (0.56) | F2RL3PARP1 | |
| SCHEMBL4403649 | 0.71 | NOS3 (0.38) | CCR1CCR5CCR8BRD4KAT2B | |
| SCHEMBL22305920 | 0.70 | BRD4 (0.38) | BRD9BRD7BRD4 | |
| SCHEMBL22114153 | 0.69 | BRD9 (0.49) | BRD9BRD7BRD4 | |
| SCHEMBL5986099 | 0.69 | BRD9 (0.45) | BRD9BRD7BRD4 | |
| SCHEMBL22306188 | 0.69 | BRD9 (0.49) | BRD9BRD7BRD4 | |
| SCHEMBL20795395 | 0.69 | BRD9 (0.49) | F2RL3BRD9BRD4PARP1KAT2B | |
| SCHEMBL15206048 | 0.68 | PIM1 (0.36) | BRD9BRD4 | |
| SCHEMBL20928236 | 0.67 | CCR1 (0.52) | CCR1CCR5CCR8PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |