Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14340738 | 0.95 | PTPN1 (0.49) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL225260 | 0.92 | PTPN1 (0.65) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL225261 | 0.92 | PTPN1 (0.65) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL222431 | 0.90 | MAPT (0.52) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL222432 | 0.90 | MAPT (0.52) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL12204878 | 0.78 | PTPN1 (0.79) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL225037 | 0.77 | MAPT (0.61) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL12204850 | 0.77 | PTPN1 (0.52) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL222957 | 0.76 | PTPN1 (0.84) | PTPN1MAPK1GAAHTTALDH1A1 | |
| SCHEMBL222958 | 0.76 | PTPN1 (0.84) | PTPN1MAPK1GAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004386-A1 | CONJUGATED THIOPHENES HAVING CONDUCTING PROPERTIES AND SYNTHESIS OF SAME | UNIVERSITE DE MONTREAL (CA) | 2012-01-05 | — | — | US | disclosed |
| US-8034895-B2 | Conjugated thiophenes having conducting properties and synthesis of same | Université de Montréal (CA) | 2011-10-11 | — | — | US | disclosed |
| US-20070287842-A1 | Conjugated Thiophenes Having Conducting Properties and Synthesis of Same | UNIVERSITE DE MONTREAL (CA) | 2007-12-13 | — | — | US | disclosed |
| WO-2005073265-A1 | CONJUGATED THIOPHENES HAVING CONDUCTING PROPERTIES AND SYNTHESIS OF SAME | UNIVERSITE DE MONTREAL (CA) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287842-A1 | Conjugated Thiophenes Having Conducting Properties and Synthesis of Same | DDT, DDC, TRPA1 | PTPN1 945/4885MAPK1 3491/4885GAA 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.