Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.57 |
| ▸ | LPL | P06858 | 11/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464245 | 0.86 | LIPG (0.56) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL19464259 | 0.81 | LIPG (0.61) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL1744642 | 0.81 | LIPG (0.60) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL14750157 | 0.80 | LIPG (0.50) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL13703570 | 0.80 | LIPG (0.58) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL28693280 | 0.80 | LIPG (0.58) | LIPGLPLDGAT1TDP2ESR2 | |
| SCHEMBL20768149 | 0.79 | LIPG (0.62) | LIPGLPLDGAT1TDP2F11 | |
| SCHEMBL18332737 | 0.79 | LIPG (0.69) | LIPGLPLDGAT1ESR2F11 | |
| SCHEMBL12215735 | 0.76 | LIPG (0.80) | LIPGLPLDGAT1ESR2F11 | |
| SCHEMBL30477495 | 0.76 | LIPG (0.80) | LIPGLPLDGAT1ESR2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |