Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792535 | 0.84 | — | — | |
| SCHEMBL24611784 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL14198854 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL17225975 | 0.82 | EPHX1 (0.62) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16384294 | 0.82 | MEN1 (0.68) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31036065 | 0.82 | MEN1 (0.68) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16500486 | 0.82 | MEN1 (0.68) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16853212 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL13033212 | 0.81 | TSHR (0.43) | TSHRALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22418053 | 0.80 | TSHR (0.68) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |