Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290115 | 0.81 | BRD4 (0.34) | BRD4PNMTHTR2CMEN1GABRA1 | |
| SCHEMBL25604386 | 0.79 | BRD4 (0.37) | BRD4PNMTHTR2CMEN1GABRA1 | |
| SCHEMBL22290131 | 0.78 | BRD4 (0.36) | BRD4PNMTHTR2CMEN1GABRA1 | |
| SCHEMBL21904897 | 0.69 | PNMT (0.42) | PNMT | |
| SCHEMBL4793244 | 0.69 | CD44 (0.42) | BRD4PNMTHTR2CMEN1GABRA1 | |
| SCHEMBL25606981 | 0.68 | BRD4 (0.41) | BRD4 | |
| SCHEMBL21363443 | 0.68 | SRC (0.38) | HTR2CSIGMAR1 | |
| SCHEMBL25607096 | 0.66 | BRD4 (0.36) | BRD4 | |
| SCHEMBL1968864 | 0.62 | GABRA1 (0.36) | PNMTHTR2CMEN1GABRA1CYP2C19 | |
| SCHEMBL9836925 | 0.60 | PARP1 (0.41) | HTR2CHTR2APARP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |