Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473070 | 1.00 | HPGD (0.34) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22308214 | 0.88 | HPGD (0.36) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22308215 | 0.83 | EGFR (0.33) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29473089 | 0.83 | EGFR (0.33) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22307226 | 0.81 | CDK9 (0.36) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29473228 | 0.81 | CDK9 (0.36) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31521803 | 0.79 | MMP2 (0.39) | HPGDSMN1; SMN2F2F10PLG | |
| SCHEMBL22307190 | 0.79 | MMP2 (0.39) | HPGDSMN1; SMN2F2F10PLG | |
| SCHEMBL29473086 | 0.79 | MMP2 (0.39) | HPGDSMN1; SMN2F2F10PLG | |
| SCHEMBL22308221 | 0.74 | EGFR (0.33) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365995-A | Immunomodulator, composition and method thereof | 贝达药业股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| WO-2020156323-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |