Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419583 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3458343 | 0.83 | — | — | |
| SCHEMBL23152669 | 0.83 | — | — | |
| SCHEMBL6575662 | 0.81 | — | — | |
| SCHEMBL20508886 | 0.81 | — | — | |
| SCHEMBL2991432 | 0.81 | — | — | |
| SCHEMBL29350329 | 0.80 | PTGS1 (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2597732 | 0.78 | KDM4E (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrogen Sulfide SCHEMBL2230859 | 0.78 | FOLH1 (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL157552 | 0.78 | KDM4E (0.50) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807399-B2 | Methods for detecting thiol-containing nucleotide diphosphates with thiol-reactive fluorescent reagents | MARQUETTE UNIVERSITY (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090325179-A1 | Methods for Detecting Thiol-Containing Nucleotide Diphosphates with Thiol-Reactive Fluorescent Reagents | MARQUETTE UNIVERSITY (US) | 2009-12-31 | — | — | US | disclosed |
| US-7585643-B2 | Reacting a mixture that contains an ATP analog such as ATP beta S to form an ADP analog such as ADP beta S if kinase activity is present in the mixture | MARQUETTE UNIVERSITY (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070054343-A1 | Use of thiol-reactive reagents for detecting enzyme activity | MARQUETTE UNIVERSITY | 2007-03-08 | — | — | US | disclosed |