SCHEMBL22308641

SCHEMBL22308641

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4cccc(-c5cccc(-c6cc(-c7ccc(-c8cccc9c8oc8ccccc89)cc7)nc(-c7ccccc7)n6)c5)c4)nc(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)n3)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
MAPT P10636 8/20 0.37
KMT2A Q03164 6/20 0.37
ALDH1A1 P00352 6/20 0.37
MEN1 O00255 5/20 0.37
HPGD P15428 4/20 0.37
LMNA P02545 4/20 0.37
KDM4E B2RXH2 3/20 0.37
GLA P06280 1/20 0.37
GGPS1 O95749 1/20 0.34
PRKDC P78527 1/20 0.34
NTSR1 P30989 1/20 0.33
TSHR P16473 2/20 0.33
POLB P06746 2/20 0.33
NPSR1 Q6W5P4 2/20 0.32
PDK2 Q15119 1/20 0.32
ACACA Q13085 2/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
USP2 O75604 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22308638 1.00 ALOX5 (0.40) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL22309371 0.98 ALOX5 (0.38) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL22309366 0.97 ALOX5 (0.38) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL15501838 0.96 ALOX5 (0.43) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL22308640 0.95 ALOX5 (0.39) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL15501650 0.95 ALOX5 (0.42) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL17899194 0.95 ALOX5 (0.42) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL15501928 0.95 ALOX5 (0.42) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL24700887 0.94 ALOX5 (0.37) ALOX5MAPTKMT2AALDH1A1MEN1
SCHEMBL17899229 0.93 ALOX5 (0.41) ALOX5MAPTKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917910-B2 Organic compound and organic electroluminescent device using the same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-11917910-B2 Organic compound and organic electroluminescent device using the same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-20200251659-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200251659-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME VDAC1, OR10J3, PIEZO1 ALOX5 775/4885MAPT 660/4885KMT2A 2549/4885
US-11917910-B2 Organic compound and organic electroluminescent device using the same VDAC1, OR10J3, PIEZO1 ALOX5 775/4885MAPT 660/4885KMT2A 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.