SCHEMBL22308778

SCHEMBL22308778

c1ccc(-c2nc(-c3cccc(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)c3)cc(-c3ccc4oc5ccccc5c4c3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 5/20 0.49
HPGD P15428 5/20 0.49
MAPT P10636 5/20 0.49
KDM4E B2RXH2 3/20 0.49
LMNA P02545 2/20 0.49
GLA P06280 1/20 0.49
PLA2G2A P14555 4/20 0.47
PLA2G4A P47712 4/20 0.47
PLA2G10 O15496 1/20 0.47
NTSR1 P30989 1/20 0.44
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CHEK2 O96017 1/20 0.40
PTPRF P10586 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23268801 0.99 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL22308591 0.99 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL22113759 0.99 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL23268831 0.97 KMT2A (0.52) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15501298 0.97 MEN1 (0.49) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL21108983 0.96 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15501558 0.96 MEN1 (0.48) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15501577 0.96 PLA2G2A (0.46) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15501416 0.96 MEN1 (0.48) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15501409 0.94 PLA2G2A (0.45) MEN1KMT2AALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917910-B2 Organic compound and organic electroluminescent device using the same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-11917910-B2 Organic compound and organic electroluminescent device using the same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
US-20200251659-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200251659-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME VDAC1, OR10J3, PIEZO1 MEN1 2484/4885KMT2A 2549/4885ALDH1A1 644/4885
US-11917910-B2 Organic compound and organic electroluminescent device using the same VDAC1, OR10J3, PIEZO1 MEN1 2484/4885KMT2A 2549/4885ALDH1A1 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.