Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 9/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CDC14B | O60729 | 1/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21659069 | 0.92 | ALOX5 (0.55) | ALOX5PRKDCGGPS1PIK3CDPIK3CB | |
| SCHEMBL17057228 | 0.90 | ALOX5 (0.52) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL21907404 | 0.90 | ALOX5 (0.43) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL21432779 | 0.90 | ALOX5 (0.43) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL21433058 | 0.90 | ALOX5 (0.46) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL21427987 | 0.89 | ALOX5 (0.47) | ALOX5PRKDCGGPS1PIK3CDPIK3CB | |
| SCHEMBL24171093 | 0.88 | ALOX5 (0.59) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL21658814 | 0.88 | ALOX5 (0.42) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL23349563 | 0.88 | ALOX5 (0.42) | ALOX5LIMK1PRKDCGGPS1PIK3CD | |
| SCHEMBL17057163 | 0.88 | ALOX5 (0.56) | ALOX5LIMK1PRKDCGGPS1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200251660-A1 | MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200251660-A1 | MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES | DDT, ESD, ETFA | ALOX5 349/4885LIMK1 1665/4885PRKDC 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.