Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17369162 | 0.87 | CTSK (0.61) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16379313 | 0.87 | CTSK (0.61) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17449759 | 0.87 | CTSK (0.61) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL15312451 | 0.84 | CTSK (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18516253 | 0.83 | CTSK (0.45) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22156688 | 0.83 | CTSK (0.45) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18438966 | 0.83 | CTSK (0.43) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18438964 | 0.83 | CTSK (0.43) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14079862 | 0.80 | CTSK (0.45) | CTSKCTSSTDP1ATMPOLB | |
| SCHEMBL11977584 | 0.80 | CTSK (0.45) | CTSKCTSSTDP1ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157177-A1 | PSMA BINDING DUAL MODE RADIOTRACER AND THERAPEUTIC | Technische Universität München (DE) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020157184-A1 | CANCER DIAGNOSTIC IMAGING AGENTS | Technische Universität München (DE) | 2020-08-06 | — | — | WO | disclosed |